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Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Bacteroides thetaiotaomicron Strains

Genomic differences between gut-resident bacterial strains likely underlie significant interindividual variation in microbiome function. Traditional methods of determining community composition, such as 16S rRNA gene amplicon sequencing, fail to capture this functional diversity. Metagenomic approac...

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Detalles Bibliográficos
Autores principales: Joglekar, Payal, Sonnenburg, Erica D., Higginbottom, Steven K., Earle, Kristen A., Morland, Carl, Shapiro-Ward, Sarah, Bolam, David N., Sonnenburg, Justin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967196/
https://www.ncbi.nlm.nih.gov/pubmed/29794055
http://dx.doi.org/10.1128/mSphereDirect.00185-18