Use of succinic & oxalic acid in reducing the dosage of colistin against New Delhi metallo-β-lactamase-1 bacteria

BACKGROUND & OBJECTIVES: New Delhi metallo-β-lactamase 1 (NDM-1) cleaves the beta-lactam ring, and confers bacterial resistance against most of the beta-lactam antibiotics, except tigecycline and colistin. Among these two antibiotics, colistin is considered toxic, and therefore, its clinical use...

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Detalles Bibliográficos
Autores principales: Kumar, Ravichandiran, Chandar, Brinda, Parani, Madasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967224/
https://www.ncbi.nlm.nih.gov/pubmed/29749367
http://dx.doi.org/10.4103/ijmr.IJMR_1407_16

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