Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation

Myotube formation by fusion of myoblasts and subsequent elongation of the syncytia is essential for skeletal muscle formation. However, molecules that regulate myotube formation remain elusive. Here we identify PIEZO1, a mechanosensitive Ca(2+) channel, as a key regulator of myotube formation. Durin...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Masaki, Hara, Yuji, Okuda, Masaki, Itoh, Karin, Nishioka, Ryotaro, Shiomi, Akifumi, Nagao, Kohjiro, Mori, Masayuki, Mori, Yasuo, Ikenouchi, Junichi, Suzuki, Ryo, Tanaka, Motomu, Ohwada, Tomohiko, Aoki, Junken, Kanagawa, Motoi, Toda, Tatsushi, Nagata, Yosuke, Matsuda, Ryoichi, Takayama, Yasunori, Tominaga, Makoto, Umeda, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967302/
https://www.ncbi.nlm.nih.gov/pubmed/29799007
http://dx.doi.org/10.1038/s41467-018-04436-w

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