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Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y(1) and P2Y(12) receptors

Many hemorheologic Traditional Chinese Medicines (TCMs) that are widely-used clinically lack molecular mechanisms of action. We hypothesized that some of the active components of hemorheologic TCMs may function through targeting prothrombotic P2Y(1) and/or P2Y(12) receptors. The interactions between...

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Detalles Bibliográficos
Autores principales: Liu, Xuyang, Gao, Zhan-Guo, Wu, Yiran, Stevens, Raymond C., Jacobson, Kenneth A., Zhao, Suwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967328/
https://www.ncbi.nlm.nih.gov/pubmed/29795391
http://dx.doi.org/10.1038/s41598-018-26577-0