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Improving draft genome contiguity with reference-derived in silico mate-pair libraries
BACKGROUND: Contiguous genome assemblies are a highly valued biological resource because of the higher number of completely annotated genes and genomic elements that are usable compared to fragmented draft genomes. Nonetheless, contiguity is difficult to obtain if only low coverage data and/or only...
Autores principales: | Grau, José Horacio, Hackl, Thomas, Koepfli, Klaus-Peter, Hofreiter, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967465/ https://www.ncbi.nlm.nih.gov/pubmed/29688527 http://dx.doi.org/10.1093/gigascience/giy029 |
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