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New Methods for Inferring the Distribution of Fitness Effects for INDELs and SNPs

Small insertions and deletions (INDELs; ≤50 bp) are the most common type of variability after single nucleotide polymorphism (SNP). However, compared with SNPs, we know little about the distribution of fitness effects (DFE) of new INDEL mutations and how prevalent adaptive INDEL substitutions are. S...

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Detalles Bibliográficos
Autores principales: Barton, Henry J, Zeng, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967470/
https://www.ncbi.nlm.nih.gov/pubmed/29635416
http://dx.doi.org/10.1093/molbev/msy054