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Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

The immunomodulatory actions of parasitic helminth excretory-secretory (ES) products that serendipitously protect against development of chronic inflammatory disorders are well established: however, knowledge of the interaction between ES products and the host musculoskeletal system in such diseases...

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Detalles Bibliográficos
Autores principales: Doonan, James, Lumb, Felicity E., Pineda, Miguel A., Tarafdar, Anuradha, Crowe, Jenny, Khan, Aneesah M., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967578/
https://www.ncbi.nlm.nih.gov/pubmed/29867986
http://dx.doi.org/10.3389/fimmu.2018.01016