Cargando…
Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis
The immunomodulatory actions of parasitic helminth excretory-secretory (ES) products that serendipitously protect against development of chronic inflammatory disorders are well established: however, knowledge of the interaction between ES products and the host musculoskeletal system in such diseases...
Autores principales: | Doonan, James, Lumb, Felicity E., Pineda, Miguel A., Tarafdar, Anuradha, Crowe, Jenny, Khan, Aneesah M., Suckling, Colin J., Harnett, Margaret M., Harnett, William |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967578/ https://www.ncbi.nlm.nih.gov/pubmed/29867986 http://dx.doi.org/10.3389/fimmu.2018.01016 |
Ejemplares similares
-
The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
por: Doonan, James, et al.
Publicado: (2019) -
Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62
por: Lumb, Felicity E., et al.
Publicado: (2017) -
Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts
por: Corbet, Marlene, et al.
Publicado: (2021) -
The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing
por: Crowe, Jenny, et al.
Publicado: (2020) -
The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing
por: Harnett, Margaret M., et al.
Publicado: (2022)