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Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol
Pulmonary fibrosis is a chronic and irreversible scarring disease in the lung with poor prognosis. Few therapies are available; therefore it is critical to identify new therapeutic targets. Our lab has previously identified the enzyme lactate dehydrogenase-A (LDHA) as a potential therapeutic target...
Autores principales: | Judge, Jennifer L., Nagel, David J., Owens, Kristina M., Rackow, Ashley, Phipps, Richard P., Sime, Patricia J., Kottmann, R. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967738/ https://www.ncbi.nlm.nih.gov/pubmed/29795645 http://dx.doi.org/10.1371/journal.pone.0197936 |
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