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Decreased DNA methylation of a CpG site in the HBAP1 gene in plasma DNA from pregnant women

OBJECTIVE: The objective of this study is to identify potential CpG site(s) or DNA methylation pattern(s) in the pseudo α-globin 1 gene (HBAP1 gene), the gene which locates in α-thalassemia-1 deletion mutation, to differentiate plasma DNA between pregnant and non-pregnant women. METHOD: DNA methylat...

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Detalles Bibliográficos
Autores principales: Pangeson, Tanapat, Sanguansermsri, Torpong, Mahingsa, Khwanruedee, Sanguansermsri, Phanchana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967787/
https://www.ncbi.nlm.nih.gov/pubmed/29795670
http://dx.doi.org/10.1371/journal.pone.0198165