Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations

The type C feruloyl esterase FoFaeC from Fusarium oxysporum is a newly discovered enzyme with high potential for use in the hydrolysis of lignocellulosic biomass but it shows low activity towards sinapates. In this work, small molecule docking simulations were employed in order to identify important...

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Detalles Bibliográficos
Autores principales: Antonopoulou, Io, Hunt, Cameron, Cerullo, Gabriella, Varriale, Simona, Gerogianni, Alexandra, Faraco, Vincenza, Rova, Ulrika, Christakopoulos, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967792/
https://www.ncbi.nlm.nih.gov/pubmed/29795702
http://dx.doi.org/10.1371/journal.pone.0198127

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