Cargando…

Structure of the human lipid-gated cation channel TRPC3

The TRPC channels are crucially involved in store-operated calcium entry and calcium homeostasis, and they are implicated in human diseases such as neurodegenerative disease, cardiac hypertrophy, and spinocerebellar ataxia. We present a structure of the full-length human TRPC3, a lipid-gated TRPC me...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Chen, Choi, Wooyoung, Sun, Weinan, Du, Juan, Lü, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967863/
https://www.ncbi.nlm.nih.gov/pubmed/29726814
http://dx.doi.org/10.7554/eLife.36852