Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

BACKGROUND: Gut microbiota-derived short-chain fatty acids (SCFAs) have been associated with beneficial metabolic effects. However, the direct effect of oral butyrate on metabolic parameters in humans has never been studied. In this first in men pilot study, we thus treated both lean and metabolic s...

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Detalles Bibliográficos
Autores principales: Bouter, KEC, Bakker, GJ, Levin, E., Hartstra, AV, Kootte, RS, Udayappan, SD, Katiraei, S., Bahler, L., Gilijamse, P. W., Tremaroli, V., Stahlman, M., Holleman, F., van Riel, N. A. W., Verberne, HJ, Romijn, JA, Dallinga-Thie, GM, Serlie, MJ, Ackermans, MT, Kemper, EM, Willems van Dijk, K., Backhed, F., Groen, AK, Nieuwdorp, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968024/
https://www.ncbi.nlm.nih.gov/pubmed/29799027
http://dx.doi.org/10.1038/s41424-018-0025-4

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