Cargando…

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

Metabolic rewiring and the consequent production of reactive oxygen species (ROS) are necessary to promote tumorigenesis. At the nexus of these cellular processes is the aberrant regulation of oncogenic signaling cascades such as the phosphoinositide 3-kinase and AKT (PI3K/Akt) pathway, which is one...

Descripción completa

Detalles Bibliográficos
Autores principales: Koundouros, Nikos, Poulogiannis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968394/
https://www.ncbi.nlm.nih.gov/pubmed/29868481
http://dx.doi.org/10.3389/fonc.2018.00160