Cargando…

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

Metabolic rewiring and the consequent production of reactive oxygen species (ROS) are necessary to promote tumorigenesis. At the nexus of these cellular processes is the aberrant regulation of oncogenic signaling cascades such as the phosphoinositide 3-kinase and AKT (PI3K/Akt) pathway, which is one...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koundouros, Nikos, Poulogiannis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968394/ https://www.ncbi.nlm.nih.gov/pubmed/29868481 http://dx.doi.org/10.3389/fonc.2018.00160

Ejemplares similares

Reprogramming of fatty acid metabolism in cancer
por: Koundouros, Nikos, et al.
Publicado: (2019)

PARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN
por: Gupta, Amit, et al.
Publicado: (2017)

The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infection
por: Cooray, Samantha
Publicado: (2007)

DNA Damage, Repair, and Cancer Metabolism
por: Turgeon, Marc-Olivier, et al.
Publicado: (2018)

Therapeutic Potential of Autophagy in Glioblastoma Treatment With Phosphoinositide 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway Inhibitors
por: Xia, Qin, et al.
Publicado: (2020)

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
por: McGonnell, Imelda M., et al.
Publicado: (2012)

Arsenite-induced stress signaling: Modulation of the phosphoinositide 3′-kinase/Akt/FoxO signaling cascade()
por: Hamann, Ingrit, et al.
Publicado: (2013)

Signaling Pathways Regulating Redox Balance in Cancer Metabolism
por: De Santis, Maria Chiara, et al.
Publicado: (2018)

Propofol mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT
por: Shravah, Jayant, et al.
Publicado: (2014)

Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation
por: van Weverwijk, Antoinette, et al.
Publicado: (2019)

Lysophosphatidic Acid Signalling Regulates Human Sperm Viability via the Phosphoinositide 3-Kinase/AKT Pathway
por: Liao, Hao-Yu, et al.
Publicado: (2023)

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus
por: Saeed, Mohammad F., et al.
Publicado: (2008)

Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway
por: JUNG, CHAN-HUN, et al.
Publicado: (2013)

The Role of Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation
por: Cahill, Catherine M., et al.
Publicado: (2012)

Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals
por: Mckenzie, Grahame, et al.
Publicado: (2006)

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation
por: Gupta, Amit, et al.
Publicado: (2017)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Editorial: Redox and Metabolic Circuits in Cancer
por: Rizza, Salvatore, et al.
Publicado: (2018)

Adenylate Kinase and Metabolic Signaling in Cancer Cells
por: Klepinin, Aleksandr, et al.
Publicado: (2020)

The phosphoinositide 3-kinase pathway and therapy resistance in cancer
por: Brown, Kristin K., et al.
Publicado: (2015)

Phosphoinositide 3-Kinase signaling pathway: the key to cell proliferation and death
por: Peacock, Justin
Publicado: (2007)

Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells
por: Condliffe, Alison M, et al.
Publicado: (2000)

Phosphoinositide 3-kinase at the crossroad between endocytosis and signaling of cytokine receptors
por: Basquin, Cyril, et al.
Publicado: (2013)

Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling
por: Lin, Richard Z., et al.
Publicado: (2019)

Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation
por: Chu, Erskine, et al.
Publicado: (2021)

TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway
por: Wang, Lin, et al.
Publicado: (2018)

Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway
por: He, Zhengyu, et al.
Publicado: (2012)

Berberine Induced Apoptosis of Human Osteosarcoma Cells by Inhibiting Phosphoinositide 3 Kinase/Protein Kinase B (PI3K/Akt) Signal Pathway Activation
por: CHEN, Zhi-Ze
Publicado: (2016)

Editorial: Redox Potential and Metabolic Behavior in Gastrointestinal Cancers
por: Biagioni, Alessio, et al.
Publicado: (2022)

Junction of the redox dynamic, orchestra of signaling, and altered metabolism in regulation of T- cell lymphoma
por: Singh, Shantanu, et al.
Publicado: (2023)

The integrative bioinformatics approaches to predict the xanthohumol as anti-breast cancer molecule: Targeting cancer cells signaling PI3K and AKT kinase pathway
por: Gupta, Kartikey Kumar, et al.
Publicado: (2022)

Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia
por: Shey, Susan, et al.
Publicado: (2021)

Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases
por: Finlay, David K.
Publicado: (2012)

Ephrin type-A receptor 2 regulates sensitivity to paclitaxel in nasopharyngeal carcinoma via the phosphoinositide 3-kinase/Akt signalling pathway
por: WANG, YUNYUN, et al.
Publicado: (2015)

Inhibition of Phosphoinositide 3-Kinase Gamma Protects Endothelial Cells via the Akt Signaling Pathway in Sepsis-Induced Acute Kidney Injury
por: Li, Han, et al.
Publicado: (2022)

Redox integration of signaling and metabolism in a head and neck cancer model of radiation resistance using COSM(RO)
por: Ji, Zhiwei, et al.
Publicado: (2023)

Targeting PI3K/Akt/mTOR Signaling in Cancer
por: Porta, Camillo, et al.
Publicado: (2014)

Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas
por: Janus, Joanna M., et al.
Publicado: (2017)

Inositol Polyphosphate-Based Compounds as Inhibitors of Phosphoinositide 3-Kinase-Dependent Signaling
por: Maffucci, Tania, et al.
Publicado: (2020)

Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?
por: Fry, Michael John
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_2mrktv6bu0is7ml1ed8hr58jo7