Putative bovine topological association domains and CTCF binding motifs can reduce the search space for causative regulatory variants of complex traits

BACKGROUND: Topological association domains (TADs) are chromosomal domains characterised by frequent internal DNA-DNA interactions. The transcription factor CTCF binds to conserved DNA sequence patterns called CTCF binding motifs to either prohibit or facilitate chromosomal interactions. TADs and CT...

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Detalles Bibliográficos
Autores principales: Wang, Min, Hancock, Timothy P., Chamberlain, Amanda J., Vander Jagt, Christy J., Pryce, Jennie E., Cocks, Benjamin G., Goddard, Mike E., Hayes, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968476/
https://www.ncbi.nlm.nih.gov/pubmed/29793448
http://dx.doi.org/10.1186/s12864-018-4800-0

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