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Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation

BACKGROUND: Repurposing existing medications for antineoplastic purposes can provide a safe, cost-effective, and efficacious means to further augment available cancer care. Clinical and preclinical studies suggest a role for the ß-adrenergic antagonist (ß-blocker) propranolol in reducing rates of tu...

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Detalles Bibliográficos
Autores principales:	Knight, Jennifer M., Kerswill, Stephanie A., Hari, Parameswaran, Cole, Steve W., Logan, Brent R., D’Souza, Anita, Shah, Nirav N., Horowitz, Mary M., Stolley, Melinda R., Sloan, Erica K., Giles, Karen E., Costanzo, Erin S., Hamadani, Mehdi, Chhabra, Saurabh, Dhakal, Binod, Rizzo, J. Douglas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968588/ https://www.ncbi.nlm.nih.gov/pubmed/29793446 http://dx.doi.org/10.1186/s12885-018-4509-0

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