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Intrauterine hyperglycemia exposure results in intergenerational inheritance via DNA methylation reprogramming on F1 PGCs

BACKGROUND: The existing reports about intergenerational or transgenerational effects of intrauterine hyperglycemia have included both intrauterine and postnatal metabolic exposure factors, while the impact of intrauterine hyperglycemia per se has not been assessed alone. A number of studies suggest...

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Detalles Bibliográficos
Autores principales: Ren, Jun, Cheng, Yi, Ming, Zhen-Hua, Dong, Xin-Yan, Zhou, Yu-Zhong, Ding, Guo-Lian, Pang, Hai-Yan, Rahman, Tanzil Ur, Akbar, Rubab, Huang, He-Feng, Sheng, Jian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968593/
https://www.ncbi.nlm.nih.gov/pubmed/29801514
http://dx.doi.org/10.1186/s13072-018-0192-2

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