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Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration

Several molecular pathways are currently being targeted in attempts to develop disease-modifying therapies to slow down neurodegeneration in Parkinson’s disease. Failure of cellular energy metabolism has long been implicated in sporadic Parkinson’s disease and recent research on rare inherited forms...

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Detalles Bibliográficos
Autores principales:	Quansah, Emmanuel, Peelaerts, Wouter, Langston, J. William, Simon, David K., Colca, Jerry, Brundin, Patrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968614/ https://www.ncbi.nlm.nih.gov/pubmed/29793507 http://dx.doi.org/10.1186/s13024-018-0260-x

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