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Expression and significance of the Hedgehog signal transduction pathway in oxygen-induced retinal neovascularization in mice
AIM: The aim of the study was to investigate the signal transduction mechanism of Hedgehog–vascular endothelial growth factor in oxygen-induced retinopathy (OIR) and the effects of cyclopamine on OIR. METHODS: An OIR model was established in C57BL/6J mice exposed to hyperoxia. Two hundred mice were...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968796/ https://www.ncbi.nlm.nih.gov/pubmed/29861625 http://dx.doi.org/10.2147/DDDT.S149594 |