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Effects of human relaxin-2 (serelaxin) on hypoxic pulmonary vasoconstriction during acute hypoxia in a sheep model

PURPOSE: Hypoxia induces pulmonary vasoconstriction with a subsequent increase of pulmonary artery pressure (PAP), which can result in pulmonary hypertension. Serelaxin has shown an increase of pulmonary hemodynamic parameters after serelaxin injection. We therefore investigated the response of pulm...

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Detalles Bibliográficos
Autores principales:	Schiffner, René, Nistor, Marius, Bischoff, Sabine Juliane, Matziolis, Georg, Schmidt, Martin, Lehmann, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968803/ https://www.ncbi.nlm.nih.gov/pubmed/29862306 http://dx.doi.org/10.2147/HP.S165092

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