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CD34(−) Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34(+) Fibroblasts and Fibrocytes

PURPOSE: Orbital fibroblasts from patients with Graves' disease (GD-OF) express many different cytokines when treated with bovine thyrotropin (bTSH). The present study aimed to determine why TNF-α cannot be induced by bTSH in GD-OF. METHODS: Fibrocytes and GD-OFs were cultivated from donors who...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Atkins, Stephen J., Fernando, Roshini, Trierweiler, Aaron, Mester, Tünde, Grisolia, Ana Beatriz Diniz, Mou, Pei, Novaes, Priscila, Smith, Terry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968835/
https://www.ncbi.nlm.nih.gov/pubmed/29847668
http://dx.doi.org/10.1167/iovs.18-23951