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Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats

PURPOSE: To investigate whether sheets of retina organoids derived from human embryonic stem cells (hESCs) can differentiate, integrate, and improve visual function in an immunodeficient rat model of severe retinal degeneration (RD). METHODS: 3D hESC-derived retina organoids were analyzed by quantit...

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Detalles Bibliográficos
Autores principales:	McLelland, Bryce T., Lin, Bin, Mathur, Anuradha, Aramant, Robert B., Thomas, Biju B., Nistor, Gabriel, Keirstead, Hans S., Seiler, Magdalene J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968836/ https://www.ncbi.nlm.nih.gov/pubmed/29847666 http://dx.doi.org/10.1167/iovs.17-23646

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