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The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium

Cell density has profound impacts on the cell culture practices of human pluripotent stem cells. The regulation of cell growth, cell death, pluripotency and differentiation converge at high density, but it is largely unknown how different regulatory mechanisms act at this stage. We use a chemically...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Ren, Zhili, Lu, Kai, Song, Chengcheng, Cheung, Edwin Chong Wing, Zhou, Zhou, Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968841/
https://www.ncbi.nlm.nih.gov/pubmed/29805300
http://dx.doi.org/10.7150/ijbs.24681

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