Cargando…
Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection
BACKGROUND: Alveolar macrophages are sentinels of the airways that must exhibit immune restraint to innocuous antigens but elicit a robust inflammatory response to pathogenic threats. How distinction between these dichotomous functions is controlled is poorly defined. Neutrophils are the first respo...
Autores principales: | Peiró, Teresa, Patel, Dhiren F, Akthar, Samia, Gregory, Lisa G, Pyle, Chloe J, Harker, James A, Birrell, Mark A, Lloyd, Clare M, Snelgrove, Robert J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969338/ https://www.ncbi.nlm.nih.gov/pubmed/29079611 http://dx.doi.org/10.1136/thoraxjnl-2017-210010 |
Ejemplares similares
-
Placental mesenchymal stem cells boost M2 alveolar over M1 bone marrow macrophages via IL-1β in Klebsiella-mediated acute respiratory distress syndrome
por: Wang, Li-Tzu, et al.
Publicado: (2023) -
Alternaria-derived serine protease activity drives IL-33–mediated asthma exacerbations
por: Snelgrove, Robert J., et al.
Publicado: (2014) -
Hypoxia upregulates neutrophil degranulation and potential for tissue injury
por: Hoenderdos, Kim, et al.
Publicado: (2016) -
A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
por: Tang, Francesca S M, et al.
Publicado: (2016) -
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia
por: Hatchwell, Luke, et al.
Publicado: (2015)