Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner

OBJECTIVE: Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of IBD. This clinical association is linked pathologically to the recruitment of mucosal T cells to the liver, via vascular adhesion protein (VAP)-1-dependent enzyme activity. Our aim was to examine the expr...

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Detalles Bibliográficos
Autores principales: Trivedi, Palak J, Tickle, Joseph, Vesterhus, Mette Nåmdal, Eddowes, Peter J, Bruns, Tony, Vainio, Jani, Parker, Richard, Smith, David, Liaskou, Evaggelia, Thorbjørnsen, Liv Wenche, Hirschfield, Gideon M, Auvinen, Kaisa, Hubscher, Stefan G, Salmi, Marko, Adams, David H, Weston, Chris J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969351/
https://www.ncbi.nlm.nih.gov/pubmed/28428344
http://dx.doi.org/10.1136/gutjnl-2016-312354

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