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CD14(+) CD15(−) HLA-DR(−) myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure

OBJECTIVE: Immune paresis in patients with acute-on-chronic liver failure (ACLF) accounts for infection susceptibility and increased mortality. Immunosuppressive mononuclear CD14(+)HLA-DR(−) myeloid-derived suppressor cells (M-MDSCs) have recently been identified to quell antimicrobial responses in...

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Detalles Bibliográficos
Autores principales:	Bernsmeier, Christine, Triantafyllou, Evangelos, Brenig, Robert, Lebosse, Fanny J, Singanayagam, Arjuna, Patel, Vishal C, Pop, Oltin T, Khamri, Wafa, Nathwani, Rooshi, Tidswell, Robert, Weston, Christopher J, Adams, David H, Thursz, Mark R, Wendon, Julia A, Antoniades, Charalambos Gustav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Gut 2018
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969362/ https://www.ncbi.nlm.nih.gov/pubmed/28592438 http://dx.doi.org/10.1136/gutjnl-2017-314184

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