miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression

OBJECTIVE: Both non-alcoholic fatty liver disease (NAFLD) and the multitarget complexity of microRNA (miR) suppression have recently raised much interest, but the in vivo impact and context-dependence of hepatic miR-target interactions are incompletely understood. Assessing the relative in vivo cont...

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Detalles Bibliográficos
Autores principales: Hanin, Geula, Yayon, Nadav, Tzur, Yonat, Haviv, Rotem, Bennett, Estelle R, Udi, Shiran, Krishnamoorthy, Yoganathan R, Kotsiliti, Eleni, Zangen, Rivka, Efron, Ben, Tam, Joseph, Pappo, Orit, Shteyer, Eyal, Pikarsky, Eli, Heikenwalder, Mathias, Greenberg, David S, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969364/
https://www.ncbi.nlm.nih.gov/pubmed/28381526
http://dx.doi.org/10.1136/gutjnl-2016-312869

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