Non-competitive cyclic peptides for targeting enzyme–substrate complexes

Affinity reagents are of central importance for selectively identifying proteins and investigating their interactions. We report on the development and use of cyclic peptides, identified by mRNA display-based RaPID methodology, that are selective for, and tight binders of, the human hypoxia inducibl...

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Detalles Bibliográficos
Autores principales: McAllister, T. E., Yeh, T.-L., Abboud, M. I., Leung, I. K. H., Hookway, E. S., King, O. N. F., Bhushan, B., Williams, S. T., Hopkinson, R. J., Münzel, M., Loik, N. D., Chowdhury, R., Oppermann, U., Claridge, T. D. W., Goto, Y., Suga, H., Schofield, C. J., Kawamura, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969509/
https://www.ncbi.nlm.nih.gov/pubmed/29899950
http://dx.doi.org/10.1039/c8sc00286j

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