Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK)

BACKGROUND: Activation of the AMP-activated protein kinase (AMPK) is an attractive approach for the treatment of type 2 diabetes. AMPK activation reduces glucose levels in animal models of type 2 diabetes by increasing glucose uptake in skeletal muscles and reducing hepatic glucose production. Furth...

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Detalles Bibliográficos
Autores principales: Grempler, Rolf, Wolff, Michael, Simon, Eric, Schmid, Ramona, Eisele, Claudia, Rieber, Kathrin, Fischer, Elke, Mettel, Sonja, Gabrielyan, Ogsen, Delic, Denis, Luippold, Gerd, Redeman, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969744/
https://www.ncbi.nlm.nih.gov/pubmed/29799853
http://dx.doi.org/10.1371/journal.pone.0197849

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