A panel of correlates predicts vaccine-induced protection of rats against respiratory challenge with virulent Francisella tularensis

There are no defined correlates of protection for any intracellular pathogen, including the bacterium Francisella tularensis, which causes tularemia. Evaluating vaccine efficacy against sporadic diseases like tularemia using field trials is problematic, and therefore alternative strategies to test v...

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Detalles Bibliográficos
Autores principales: De Pascalis, Roberto, Hahn, Andrew, Brook, Helen M., Ryden, Patrik, Donart, Nathaniel, Mittereder, Lara, Frey, Blake, Wu, Terry H., Elkins, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969757/
https://www.ncbi.nlm.nih.gov/pubmed/29799870
http://dx.doi.org/10.1371/journal.pone.0198140

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