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Corticostriatal circuit defects in Hoxb8 mutant mice
Hoxb8 mutant mice exhibit compulsive grooming and hair removal dysfunction similar to humans with the OCD-spectrum disorder, trichotillomania. Since, in the mouse brain, the only detectable cells that label with Hoxb8 cell lineage appear to be microglia, we suggested that defective microglia cause t...
Autores principales: | Nagarajan, Naveen, Jones, Bryan W., West, Peter J., Marc, Robert, Capecchi, Mario R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970001/ https://www.ncbi.nlm.nih.gov/pubmed/28948967 http://dx.doi.org/10.1038/mp.2017.180 |
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