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Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex
The unfolded protein response (UPR) pathway, consisting of the evolutionarily conserved Ire1 kinase/endonuclease and the bZIP transcription factor Hxl1, is critical for the pathogenicity of Cryptococcus neoformans; however, its role remains unknown in other pathogenic Cryptococcus species. Here, we...
Autores principales: | Jung, Kwang-Woo, Lee, Kyung-Tae, Averette, Anna F., Hoy, Michael J., Everitt, Jeffrey, Heitman, Joseph, Bahn, Yong-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970146/ https://www.ncbi.nlm.nih.gov/pubmed/29802329 http://dx.doi.org/10.1038/s41598-018-26405-5 |
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