Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells

Smooth muscle cells (SMCs) play a key role in atherogenesis. However, mechanisms regulating expansion and fate of pre-existing SMCs in atherosclerotic plaques remain poorly defined. Here we show that multiple SMC progenitors mix to form the aorta during development. In contrast, during atherogenesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Misra, Ashish, Feng, Zhonghui, Chandran, Rachana R., Kabir, Inamul, Rotllan, Noemi, Aryal, Binod, Sheikh, Abdul Q., Ding, Ling, Qin, Lingfeng, Fernández-Hernando, Carlos, Tellides, George, Greif, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970166/
https://www.ncbi.nlm.nih.gov/pubmed/29802249
http://dx.doi.org/10.1038/s41467-018-04447-7

Ejemplares similares

Ejemplares similares