Cargando…

Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase

Aryl-alcohol oxidase (AAO) has demonstrated to be an enzyme with a bright future ahead due to its biotechnological potential in deracemisation of chiral compounds, production of bioplastic precursors and other reactions of interest. Expanding our understanding on the AAO reaction mechanisms, through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carro, Juan, Amengual-Rigo, Pep, Sancho, Ferran, Medina, Milagros, Guallar, Victor, Ferreira, Patricia, Martínez, Angel T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970180/ https://www.ncbi.nlm.nih.gov/pubmed/29802285 http://dx.doi.org/10.1038/s41598-018-26445-x

Ejemplares similares

NetCleave: an open-source algorithm for predicting C-terminal antigen processing for MHC-I and MHC-II
por: Amengual-Rigo, Pep, et al.
Publicado: (2021)

Predicting Antibody Neutralization Efficacy in Hypermutated Epitopes Using Monte Carlo Simulations
por: Amengual-Rigo, Pep, et al.
Publicado: (2020)

Complete oxidation of hydroxymethylfurfural to furandicarboxylic acid by aryl-alcohol oxidase
por: Serrano, Ana, et al.
Publicado: (2019)

Expanding the Physiological Role of Aryl-Alcohol Flavooxidases as Quinone Reductases
por: Ferreira, Patricia, et al.
Publicado: (2023)

Pecularities and applications of aryl-alcohol oxidases from fungi
por: Urlacher, Vlada B., et al.
Publicado: (2021)

Directed evolution of the aryl-alcohol oxidase: Beyond the lab bench
por: Viña-Gonzalez, Javier, et al.
Publicado: (2020)

Substituting Tyr(138) in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation
por: Leandro, João, et al.
Publicado: (2017)

Two Fusarium copper radical oxidases with high activity on aryl alcohols
por: Cleveland, Maria, et al.
Publicado: (2021)

Insights into the FMNAT Active Site of FAD Synthase: Aromaticity Is Essential for Flavin Binding and Catalysis
por: Serrano, Ana, et al.
Publicado: (2020)

The ins and outs of vanillyl alcohol oxidase: Identification of ligand migration paths
por: Gygli, Gudrun, et al.
Publicado: (2017)

Activation of Phenylalanine Hydroxylase by Phenylalanine Does Not Require Binding in the Active Site
por: Roberts, Kenneth M., et al.
Publicado: (2014)

Multimetallic Catalysis Enabled Cross-Coupling of Aryl Bromides with Aryl Triflates
por: Ackerman, Laura K.G., et al.
Publicado: (2015)

A Conserved Acidic Residue in Phenylalanine Hydroxylase Contributes to Cofactor Affinity and Catalysis
por: Ronau, Judith A., et al.
Publicado: (2014)

Detoxification of 5-hydroxymethylfurfural by the Pleurotus ostreatus lignolytic enzymes aryl alcohol oxidase and dehydrogenase
por: Feldman, Daria, et al.
Publicado: (2015)

Dual nickel and Lewis acid catalysis for cross-electrophile coupling: the allylation of aryl halides with allylic alcohols
por: Jia, Xue-Gong, et al.
Publicado: (2017)

Merging Regiodivergent Catalysis with Atom‐Economical Radical Arylation
por: Mühlhaus, Felix, et al.
Publicado: (2019)

Aryl radical-mediated N-heterocyclic carbene catalysis
por: Matsuki, Yuki, et al.
Publicado: (2021)

Natural heterogeneous catalysis with immobilised oxidase biocatalysts
por: Mattey, Ashley P., et al.
Publicado: (2020)

An In Vitro Catalysis of Tea Polyphenols by Polyphenol Oxidase
por: Liu, Kunyi, et al.
Publicado: (2023)

Oxidation of 5‐hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601
por: Sayed, Mahmoud, et al.
Publicado: (2022)

Direct arylation and heterogeneous catalysis; ever the twain shall meet
por: Cano, Rafael, et al.
Publicado: (2015)

Asymmetric synthesis of multifunctional aryl allyl ethers by nucleophilic catalysis
por: Zhao, Shuai, et al.
Publicado: (2019)

An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1
por: Castellano, Flavia, et al.
Publicado: (2017)

C–H functionalization of amines with aryl halides by nickel-photoredox catalysis
por: Ahneman, Derek T., et al.
Publicado: (2016)

Arylation of Axially Chiral Phosphorothioate Salts by Dinuclear Pd(I) Catalysis
por: Chen, Xiang‐Yu, et al.
Publicado: (2019)

Asymmetric β-arylation of cyclopropanols enabled by photoredox and nickel dual catalysis
por: Wang, Jianhua, et al.
Publicado: (2022)

Dialumenes – aryl vs. silyl stabilisation for small molecule activation and catalysis
por: Weetman, Catherine, et al.
Publicado: (2020)

Migratory allylic arylation of 1,n-enols enabled by nickel catalysis
por: Zhao, Dan, et al.
Publicado: (2023)

Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria
por: Singh, Virender, et al.
Publicado: (2014)

Characterization of a thermotolerant aryl-alcohol oxidase from Moesziomyces antarcticus oxidizing 5-hydroxymethyl-2-furancarboxylic acid
por: Lappe, Alessa, et al.
Publicado: (2021)

Two adjacent C-terminal mutations enable expression of aryl-alcohol oxidase from Pleurotus eryngii in Pichia pastoris
por: Jankowski, Nina, et al.
Publicado: (2021)

Unravelling the Complex Denaturant and Thermal-Induced Unfolding Equilibria of Human Phenylalanine Hydroxylase
por: Conde-Giménez, María, et al.
Publicado: (2021)

Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
por: Cheng, Xiaokai, et al.
Publicado: (2019)

Intermolecular Aryl C−H Amination through Sequential Iron and Copper Catalysis
por: Mostafa, Mohamed A. B., et al.
Publicado: (2016)

Di‐Zinc–Aryl Complexes: CO(2) Insertions and Applications in Polymerisation Catalysis
por: Romain, Charles, et al.
Publicado: (2017)

Cooperative NHC and Photoredox Catalysis for the Synthesis of β‐Trifluoromethylated Alkyl Aryl Ketones
por: Meng, Qing‐Yuan, et al.
Publicado: (2020)

High-level expression of aryl-alcohol oxidase 2 from Pleurotus eryngii in Pichia pastoris for production of fragrances and bioactive precursors
por: Jankowski, Nina, et al.
Publicado: (2020)

Synthesis of thioethers, arenes and arylated benzoxazoles by transformation of the C(aryl)–C bond of aryl alcohols
por: Liu, Mingyang, et al.
Publicado: (2020)

Vanillyl alcohol oxidase from Diplodia corticola: Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives
por: Eggerichs, Daniel, et al.
Publicado: (2023)

Effects of Cavities at the Nicotinamide Binding Site of Liver Alcohol Dehydrogenase on Structure, Dynamics and Catalysis
por: Yahashiri, Atsushi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kj7tbf3gsqo6n3c84udjmqctps