The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

The majority of glioblastomas can be classified into molecular subgroups based on mutations in the TERT promoter (TERTp) and isocitrate dehydrogenase 1 or 2 (IDH). These molecular subgroups utilize distinct genetic mechanisms of telomere maintenance, either TERTp mutation leading to telomerase activ...

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Detalles Bibliográficos
Autores principales: Diplas, Bill H., He, Xujun, Brosnan-Cashman, Jacqueline A., Liu, Heng, Chen, Lee H., Wang, Zhaohui, Moure, Casey J., Killela, Patrick J., Loriaux, Daniel B., Lipp, Eric S., Greer, Paula K., Yang, Rui, Rizzo, Anthony J., Rodriguez, Fausto J., Friedman, Allan H., Friedman, Henry S., Wang, Sizhen, He, Yiping, McLendon, Roger E., Bigner, Darell D., Jiao, Yuchen, Waitkus, Matthew S., Meeker, Alan K., Yan, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970234/
https://www.ncbi.nlm.nih.gov/pubmed/29802247
http://dx.doi.org/10.1038/s41467-018-04448-6

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