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Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

The development of antibiotic resistance during treatment is a threat to patients and their environment. Insight in the mechanisms of resistance development is important for appropriate therapy and infection control. Here, we describe how through the application of mass spectrometry-based proteomics...

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Detalles Bibliográficos
Autores principales: Fleurbaaij, Frank, Henneman, Alex A., Corver, Jeroen, Knetsch, Cornelis W., Smits, Wiep Klaas, Nauta, Sjoerd T., Giera, Martin, Dragan, Irina, Kumar, Nitin, Lawley, Trevor D., Verhoeven, Aswin, van Leeuwen, Hans C., Kuijper, Ed J., Hensbergen, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970244/
https://www.ncbi.nlm.nih.gov/pubmed/29802257
http://dx.doi.org/10.1038/s41598-018-26079-z

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