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Complex Hydrogels Composed of Chitosan with Ring-opened Polyvinyl Pyrrolidone as a Gastroretentive Drug Dosage Form to Enhance the Bioavailability of Bisphosphonates

Complex hydrogels formed with chitosan (CS) and ring-opened polyvinyl pyrrolidone (roPVP) as a swellable mucoadhesive gastroretentive drug dosage form (smGRDDF) were prepared and characterized. CS/roPVP hydrogels were produced by blending CS with roPVP obtained by basic treatment of PVP. Effects of...

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Detalles Bibliográficos
Autores principales:	Su, Chia-Yu, Ho, Hsiu-O, Chen, Ying-Chen, Yu, Yu-Ting, Liu, Der-Zen, Chao, Fang-Ching, Sheu, Ming-Thau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970250/ https://www.ncbi.nlm.nih.gov/pubmed/29802291 http://dx.doi.org/10.1038/s41598-018-26432-2

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