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Fibrotic microtissue array to predict anti-fibrosis drug efficacy

Fibrosis is a severe health problem characterized by progressive stiffening of tissues which causes organ malfunction and failure. A major bottleneck in developing new anti-fibrosis therapies is the lack of in vitro models that recapitulate dynamic changes in tissue mechanics during fibrogenesis. He...

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Detalles Bibliográficos
Autores principales: Asmani, Mohammadnabi, Velumani, Sanjana, Li, Yan, Wawrzyniak, Nicole, Hsia, Isaac, Chen, Zhaowei, Hinz, Boris, Zhao, Ruogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970268/
https://www.ncbi.nlm.nih.gov/pubmed/29802256
http://dx.doi.org/10.1038/s41467-018-04336-z