A randomized controlled phase II trial of vaccination with lysate-loaded, mature dendritic cells integrated into standard radiochemotherapy of newly diagnosed glioblastoma (GlioVax): study protocol for a randomized controlled trial

BACKGROUND: Despite the combination of surgical resection, radio- and chemotherapy, median survival of glioblastoma multiforme (GBM) patients only slightly increased in the last years. Disease recurrence is definite with no effective therapy existing after tumor removal. Dendritic cell (DC) vaccinat...

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Detalles Bibliográficos
Autores principales: Rapp, Marion, Grauer, Oliver M., Kamp, Marcel, Sevens, Natalie, Zotz, Nikola, Sabel, Michael, Sorg, Rüdiger V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970474/
https://www.ncbi.nlm.nih.gov/pubmed/29801515
http://dx.doi.org/10.1186/s13063-018-2659-7

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