Gut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease

BACKGROUND: Variation in induced models of autoimmunity has been attributed to the housing environment and its effect on the gut microbiota. In Graves’ disease (GD), autoantibodies to the thyrotropin receptor (TSHR) cause autoimmune hyperthyroidism. Many GD patients develop Graves’ orbitopathy or op...

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Detalles Bibliográficos
Autores principales: Masetti, Giulia, Moshkelgosha, Sajad, Köhling, Hedda-Luise, Covelli, Danila, Banga, Jasvinder Paul, Berchner-Pfannschmidt, Utta, Horstmann, Mareike, Diaz-Cano, Salvador, Goertz, Gina-Eva, Plummer, Sue, Eckstein, Anja, Ludgate, Marian, Biscarini, Filippo, Marchesi, Julian Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970527/
https://www.ncbi.nlm.nih.gov/pubmed/29801507
http://dx.doi.org/10.1186/s40168-018-0478-4

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