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Heat-stress-modulated induction of NF-κB leads to brucellacidal pro-inflammatory defense against Brucella abortus infection in murine macrophages and in a mouse model
BACKGROUND: Brucella causes a chronic and debilitating infection that leads to great economic losses and a public health burden. In this study, we demonstrated the brucellacidal effect of heat shock mediated by the induction of pro-inflammatory cytokines, reactive oxygen species (ROS) accumulation a...
Autores principales: | Hop, Huynh Tan, Arayan, Lauren Togonon, Reyes, Alisha Wehdnesday Bernardo, Huy, Tran Xuan Ngoc, Min, Won Gi, Lee, Hu Jang, Rhee, Man Hee, Chang, Hong Hee, Kim, Suk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970535/ https://www.ncbi.nlm.nih.gov/pubmed/29801438 http://dx.doi.org/10.1186/s12866-018-1185-9 |
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