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Mxra8 is a receptor for multiple arthritogenic alphaviruses
Arthritogenic alphaviruses comprise a group of enveloped RNA viruses that are transmitted to humans by mosquitoes and cause debilitating acute and chronic musculoskeletal disease(1). The host factors required for alphavirus entry remain poorly characterized(2). Using a genome-wide CRISPR/Cas9-based...
Autores principales: | Zhang, Rong, Kim, Arthur S., Fox, Julie M., Nair, Sharmila, Basore, Katherine, Klimstra, William B., Rimkunas, Rebecca, Fong, Rachel H., Lin, Hueylie, Poddar, Subhajit, Crowe, James E., Doranz, Benjamin J., Fremont, Daved H., Diamond, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970976/ https://www.ncbi.nlm.nih.gov/pubmed/29769725 http://dx.doi.org/10.1038/s41586-018-0121-3 |
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