RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination

Class switch recombination (CSR) at the immunoglobulin heavy-chain (IgH) locus is associated with the formation of R-loop structures over switch (S) regions. While these often occur co-transcriptionally between nascent RNA and template DNA, we now show that they also form as part of a post-transcrip...

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Detalles Bibliográficos
Autores principales: Ribeiro de Almeida, Claudia, Dhir, Somdutta, Dhir, Ashish, Moghaddam, Amin E., Sattentau, Quentin, Meinhart, Anton, Proudfoot, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971202/
https://www.ncbi.nlm.nih.gov/pubmed/29731414
http://dx.doi.org/10.1016/j.molcel.2018.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971202/
https://www.ncbi.nlm.nih.gov/pubmed/29731414
http://dx.doi.org/10.1016/j.molcel.2018.04.001

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