An Optogenetic Platform for Real-Time, Single-Cell Interrogation of Stochastic Transcriptional Regulation

Transcription is a highly regulated and inherently stochastic process. The complexity of signal transduction and gene regulation makes it challenging to analyze how the dynamic activity of transcriptional regulators affects stochastic transcription. By combining a fast-acting, photo-regulatable tran...

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Detalles Bibliográficos
Autores principales: Rullan, Marc, Benzinger, Dirk, Schmidt, Gregor W., Milias-Argeitis, Andreas, Khammash, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971206/
https://www.ncbi.nlm.nih.gov/pubmed/29775585
http://dx.doi.org/10.1016/j.molcel.2018.04.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971206/
https://www.ncbi.nlm.nih.gov/pubmed/29775585
http://dx.doi.org/10.1016/j.molcel.2018.04.012

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