SIRT1 Activity in Peripheral Blood Mononuclear Cells Correlates with Altered Lung Function in Patients with Chronic Obstructive Pulmonary Disease

BACKGROUND: Oxidative stress is a recognized pathogenic mechanism in chronic obstructive pulmonary disease (COPD). Expression of the NAD(+)-dependent deacetylase Sirtuin 1 (SIRT1), an antiaging molecule with a key role in oxidative stress response, has been described as decreased in the lung of COPD...

Descripción completa

Detalles Bibliográficos
Autores principales: Conti, Valeria, Corbi, Graziamaria, Manzo, Valentina, Malangone, Paola, Vitale, Carolina, Maglio, Angelantonio, Cotugno, Roberta, Capaccio, Damiano, Marino, Luigi, Selleri, Carmine, Stellato, Cristiana, Filippelli, Amelia, Vatrella, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971245/
https://www.ncbi.nlm.nih.gov/pubmed/29861836
http://dx.doi.org/10.1155/2018/9391261

Ejemplares similares

Ejemplares similares