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Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs

To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n = 3), group I (n = 9), and group II (n = 9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s...

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Autores principales: Guan, Sishu, Liao, Zhikang, Xiang, Hongyi, Zhu, Xiyan, Wang, Zhong, Zhao, Hui, Liu, Peng, Lai, Xinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971294/
https://www.ncbi.nlm.nih.gov/pubmed/29861783
http://dx.doi.org/10.1155/2018/2321053
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author Guan, Sishu
Liao, Zhikang
Xiang, Hongyi
Zhu, Xiyan
Wang, Zhong
Zhao, Hui
Liu, Peng
Lai, Xinan
author_facet Guan, Sishu
Liao, Zhikang
Xiang, Hongyi
Zhu, Xiyan
Wang, Zhong
Zhao, Hui
Liu, Peng
Lai, Xinan
author_sort Guan, Sishu
collection PubMed
description To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n = 3), group I (n = 9), and group II (n = 9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the control group, 8 m/s in group I, and 11 m/s in group II. The kinematics and mechanical responses of the subjects were recorded and investigated. The functional change examination and the autopsies were carried out, with which the injuries were evaluated from the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS). The subjects in group I and group II experienced the caudocephalad loading at the peak pelvic accelerations of 108.92 ± 58.87 g and 139.13 g ± 78.54 g, with the peak abdomen pressures, 41.24 ± 16.89 kPa and 63.61 ± 65.83 kPa, respectively. The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. The ISS in group II was 52.71 ± 6.13, significantly higher than in group I, 26.67 ± 5.02 (p < 0.05). The thoracoabdomen CCI injuries and the mechanical response addressed presently may be useful to conduct both the prevention studies against military or civilian injuries.
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spelling pubmed-59712942018-06-03 Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs Guan, Sishu Liao, Zhikang Xiang, Hongyi Zhu, Xiyan Wang, Zhong Zhao, Hui Liu, Peng Lai, Xinan Appl Bionics Biomech Research Article To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n = 3), group I (n = 9), and group II (n = 9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the control group, 8 m/s in group I, and 11 m/s in group II. The kinematics and mechanical responses of the subjects were recorded and investigated. The functional change examination and the autopsies were carried out, with which the injuries were evaluated from the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS). The subjects in group I and group II experienced the caudocephalad loading at the peak pelvic accelerations of 108.92 ± 58.87 g and 139.13 g ± 78.54 g, with the peak abdomen pressures, 41.24 ± 16.89 kPa and 63.61 ± 65.83 kPa, respectively. The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. The ISS in group II was 52.71 ± 6.13, significantly higher than in group I, 26.67 ± 5.02 (p < 0.05). The thoracoabdomen CCI injuries and the mechanical response addressed presently may be useful to conduct both the prevention studies against military or civilian injuries. Hindawi 2018-05-10 /pmc/articles/PMC5971294/ /pubmed/29861783 http://dx.doi.org/10.1155/2018/2321053 Text en Copyright © 2018 Sishu Guan et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Guan, Sishu
Liao, Zhikang
Xiang, Hongyi
Zhu, Xiyan
Wang, Zhong
Zhao, Hui
Liu, Peng
Lai, Xinan
Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_full Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_fullStr Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_full_unstemmed Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_short Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_sort experimental study of thoracoabdominal injuries suffered from caudocephalad impacts using pigs
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971294/
https://www.ncbi.nlm.nih.gov/pubmed/29861783
http://dx.doi.org/10.1155/2018/2321053
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