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Phosphoramidates and phosphonamidates (ProTides) with antiviral activity
Following the first report on the nucleoside phosphoramidate (ProTide) prodrug approach in 1990 by Chris McGuigan, the extensive investigation of ProTide technology has begun in many laboratories. Designed with aim to overcome limitations and the key resistance mechanisms associated with nucleoside...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971382/ https://www.ncbi.nlm.nih.gov/pubmed/29792071 http://dx.doi.org/10.1177/2040206618775243 |