Cargando…

TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates

The conjugation of siderophores to antimicrobial molecules is an attractive strategy to overcome the low outer membrane permeability of Gram-negative bacteria. In this Trojan horse approach, the transport of drug conjugates is redirected via TonB-dependent receptors (TBDR), which are involved in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luscher, Alexandre, Moynié, Lucile, Auguste, Pamela Saint, Bumann, Dirk, Mazza, Lena, Pletzer, Daniel, Naismith, James H., Köhler, Thilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Mechanisms of Action: Physiological Effects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971595/ https://www.ncbi.nlm.nih.gov/pubmed/29555629 http://dx.doi.org/10.1128/AAC.00097-18

Ejemplares similares

Plant-Derived Catechols Are Substrates of TonB-Dependent Transporters and Sensitize Pseudomonas aeruginosa to Siderophore-Drug Conjugates
por: Luscher, Alexandre, et al.
Publicado: (2022)

Siderophore Cephalosporin Cefiderocol Utilizes Ferric Iron Transporter Systems for Antibacterial Activity against Pseudomonas aeruginosa
por: Ito, Akinobu, et al.
Publicado: (2016)

Experimental and computational methods to highlight behavioural variations in TonB-dependent transporter expression in Pseudomonas aeruginosa versus siderophore concentration
por: Hubert, Thibaut, et al.
Publicado: (2023)

Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin
por: Kolpen, Mette, et al.
Publicado: (2017)

Death of the TonB Shuttle Hypothesis
por: Gresock, Michael G., et al.
Publicado: (2011)

Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction
por: Chan, Derek C. K., et al.
Publicado: (2023)

Bactericidal Effect of Tomatidine-Tobramycin Combination against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa Is Enhanced by Interspecific Small-Molecule Interactions
por: Boulanger, Simon, et al.
Publicado: (2015)

TonB-dependent transporters and their occurrence in cyanobacteria
por: Mirus, Oliver, et al.
Publicado: (2009)

Catecholamine-Stimulated Growth of Aeromonas hydrophila Requires the TonB2 Energy Transduction System but Is Independent of the Amonabactin Siderophore
por: Dong, Yuhao, et al.
Publicado: (2016)

NMR structure of the C-terminal domain of TonB protein from Pseudomonas aeruginosa
por: Oeemig, Jesper S., et al.
Publicado: (2018)

TonB-Dependent Transporters Expressed by Neisseria gonorrhoeae
por: Cornelissen, Cynthia Nau, et al.
Publicado: (2011)

The Role of TonB Gene in Edwardsiella ictaluri Virulence
por: Abdelhamed, Hossam, et al.
Publicado: (2017)

Ternary structure of the outer membrane transporter FoxA with resolved signalling domain provides insights into TonB-mediated siderophore uptake
por: Josts, Inokentijs, et al.
Publicado: (2019)

Adaptive and Mutational Responses to Peptide Dendrimer Antimicrobials in Pseudomonas aeruginosa
por: Ben Jeddou, Fatma, et al.
Publicado: (2020)

The TonB Dimeric Crystal Structures Do Not Exist In Vivo
por: Postle, Kathleen, et al.
Publicado: (2010)

Bactericidal Activity of the Human Skin Fatty Acid cis-6-Hexadecanoic Acid on Staphylococcus aureus
por: Cartron, Michaël L., et al.
Publicado: (2014)

Bacterial Drug Tolerance under Clinical Conditions Is Governed by Anaerobic Adaptation but not Anaerobic Respiration
por: Hemsley, Claudia M., et al.
Publicado: (2014)

Antibiotic Streptolydigin Requires Noncatalytic Mg(2+) for Binding to RNA Polymerase
por: Zorov, Savva, et al.
Publicado: (2014)

Independence from Kinetoplast DNA Maintenance and Expression Is Associated with Multidrug Resistance in Trypanosoma brucei In Vitro
por: Gould, Matthew K., et al.
Publicado: (2014)

Antimicrobial Treatment Improves Mycobacterial Survival in Nonpermissive Growth Conditions
por: Turapov, Obolbek, et al.
Publicado: (2014)

Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus
por: Juvvadi, Praveen R., et al.
Publicado: (2015)

Eagle Effect in Nonreplicating Persister Mycobacteria
por: Wu, Mu-Lu, et al.
Publicado: (2015)

Ramoplanin at Bactericidal Concentrations Induces Bacterial Membrane Depolarization in Staphylococcus aureus
por: Cheng, Mu, et al.
Publicado: (2014)

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action
por: Vincent, Isabel M., et al.
Publicado: (2016)

Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria
por: Asli, Abdelhamid, et al.
Publicado: (2016)

Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia
por: Wang, Xiumin, et al.
Publicado: (2016)

In Vitro and In Vivo Assessments of Cardiovascular Effects with Omadacycline
por: Tanaka, S. Ken, et al.
Publicado: (2016)

Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis
por: Prosser, Gareth A., et al.
Publicado: (2016)

Development of an In Vitro Assay for Detection of Drug-Induced Resuscitation-Promoting-Factor-Dependent Mycobacteria
por: Loraine, Jessica, et al.
Publicado: (2016)

Pulmonary Deposition and Elimination of Liposomal Amikacin for Inhalation and Effect on Macrophage Function after Administration in Rats
por: Malinin, Vladimir, et al.
Publicado: (2016)

Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase
por: Kundu, Subhashri, et al.
Publicado: (2016)

Interplay between Antibiotic Efficacy and Drug-Induced Lysis Underlies Enhanced Biofilm Formation at Subinhibitory Drug Concentrations
por: Yu, Wen, et al.
Publicado: (2017)

A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum
por: Cao, Pengxing, et al.
Publicado: (2017)

Translation Elongation Factor 4 (LepA) Contributes to Tetracycline Susceptibility by Stalling Elongating Ribosomes
por: Liu, Bin, et al.
Publicado: (2018)

Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals
por: Wall, Richard J., et al.
Publicado: (2018)

Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis
por: Chen, Chao, et al.
Publicado: (2018)

Gene Expression of Pneumocystis murina after Treatment with Anidulafungin Results in Strong Signals for Sexual Reproduction, Cell Wall Integrity, and Cell Cycle Arrest, Indicating a Requirement for Ascus Formation for Proliferation
por: Cushion, Melanie T., et al.
Publicado: (2018)

Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine
por: Armitage, Emily G., et al.
Publicado: (2018)

Relationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System
por: Fernández-García, Laura, et al.
Publicado: (2018)

Novel Zinc-Attenuating Compounds as Potent Broad-Spectrum Antifungal Agents with In Vitro and In Vivo Efficacy
por: Cohrt, Karen A. O'Hanlon, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3s577lqr8j3siffsi0kd4a0v8c