Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport

Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain endothelial cells or immortalized brain endothelial cell lines. Despite their well-known differences, epithelial cell lines are also used as su...

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Detalles Bibliográficos
Autores principales: Veszelka, Szilvia, Tóth, András, Walter, Fruzsina R., Tóth, Andrea E., Gróf, Ilona, Mészáros, Mária, Bocsik, Alexandra, Hellinger, Éva, Vastag, Monika, Rákhely, Gábor, Deli, Mária A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972182/
https://www.ncbi.nlm.nih.gov/pubmed/29872378
http://dx.doi.org/10.3389/fnmol.2018.00166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972182/
https://www.ncbi.nlm.nih.gov/pubmed/29872378
http://dx.doi.org/10.3389/fnmol.2018.00166

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